Investigating the Gender Effect on the ADHD Symptoms Based on the Evaluation of Gray Matter Concentration Changes

Document Type : Original Article

Authors

1 PhD Student, Biomedical Engineering (Faculty of Engineering), Ferdowsi University of Mashhad, Mashhad, Iran

2 Associate Professor-Electrical engineering(biomedical)-Ferdowsi University of Mashhad-Mashhad-Iran

3 3INSERM, U1105, GRAMFC, Université de Picardie, CHU Nord, Amiens F80000, France

Abstract

Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most common childhood disorders, usually characterized by three main symptoms of inattention, hyperactivity, and impulsivity. Since these main symptoms and even other related symptoms of ADHD do not occur in the same severity in both males and females, so in this paper the gray matter concentration of the brain (GM) due to ADHD disease were examined, and the potential association between these two factors were explored. For this purpose, structural MRI images (164 male controls/227 male ADHDs and 129 female controls/67 female ADHDs) were extracted from the ADHD-200 database. All individuals were within the age range of 7-14 years, and the GM concentration changes of the brain due to ADHD disease in both groups of male ADHDs/male controls and female ADHDs/female controls at the voxel level (VBM) was compared through group statistical analysis.The results of this study show that, the regions of the posterior cingulate gyrus, precuneus, hippocampus, and thalamus in males and the cerebellum in females are significantly affected by ADHD disease.(پاسخ سوال 2-داور اول-جزئی) So, according to the main roles of these regions, male ADHD patients may have difficulty managing cognitive functions such as learning, emotions, memory, and visual processing. On the other hand, female ADHD patients may have difficulty paying attention compared to their healthy peers.

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TABRIZ JOURNAL OF ELECTRICAL ENGINEERING

Articles in Press, Corrected Proof
Available Online from 20 April 2024

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